A 47-year-old male patient with chronic hepatitis had a high AFP level during the follow-up period. Abdominal CT revealed at S5, which led to a diagnosis of hepatocellular carcinoma. In August 1992, partial resection of S5 was performed, and ethanol was injected into the tumor at S2. In July 1993, recurrent tumors were observed at S5 and S3. PEIT was performed for each lesion. In December 1994, multiple recurrence was observed and 4mg SMANCS was injected through the proper hepatic artery. In July 1995, another 4 mg of SMANCS was injected into the tumors. In June 1996, only a 20 mm lesion at S5 remained while the other lesions disappeared. Under general anesthesia, the patient underwent percutaneous microwave tumor coagulation. In December 1997, the AFP level was normal, snd imaging revealed disappearance of the recurrent tumor. Selection of local therapy for hepatocellular carcinoma achieved long survival in our case considering the QOL and frequent therapy administration.

症例は４７歳男性，多発性の肝細胞癌に対し肝切除，経肝動脈的エタノール注入療法を施行した。１年後，再発腫ように対しPEITを施行，さらに１年５ヶ月後多数の再発腫ように対しSMANCSを
肝動脈より注入，８ヶ月後にも注入した。１年後，２０mm病巣のみとなったため経皮的マイクロ波腫よう凝固を施行した。１年６ヶ月後，腫ようマーカー値正常，画像上再発病巣は消失した。局所療法選択の中でQOLを考慮し，複数回治療することで長期生存を得た。

Hepatocellular carcinoma, Microwave tumor coagulation 症例報告；ヒト；男性；成人；肝細胞癌；肝切除；局所投与；動脈内投与；再発；マイクロ波照射；肝臓；高分子剤；治療法；脂肪族アルコール；ポリペプチド；ペプチド系抗生物質；抗腫よう抗生物質
M.S. LIVER. MCT